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Toxic Substances Control Act
National Summary
The Toxic Substances Control Act (TSCA) was enacted in 1976 to address the increasing problems of toxic substances. Through the provisions of TSCA, the U.S. Environmental Protection Agency (EPA) can collect or require the development of information about the toxicity of particular chemicals and the extent to which people and the environment are exposed to them. Such information allows the EPA to assess whether the chemicals pose unreasonable risks to humans and the environment. TSCA provides the basis for EPA's New and Existing Chemicals programs and the basis for national programs for major chemicals of concern, such as asbestos, lead, mercury, and radon, and the foundation for other TSCA programs, such as addressing environmental issues in schools, including energy efficiency under TSCA Title V
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Forms
EPA Resources for Submitting a Premanufacture Notice (PMN)
National
Notices
Receipt of Request for Waiver From Testing
06/17/2014
National
Notices
1,4-Dioxane; Final Toxic Substances Control Act (TSCA) Risk Evaluation; Notice of Availability
01/08/2021
National
Notices
1,4-Dioxane; Supplement to the Risk Evaluation and Revised Unreasonable Risk Determination Under the Toxic Substances Control Act (TSCA); Notice of Availability
11/14/2024
National
Notices
1-Bromopropane (1-BP); Draft Toxic Substances Control Act (TSCA) Risk Evaluation and TSCA Science Advisory Committee on Chemicals (SACC) Meetings; Notice of Availability and Public Meetings
08/12/2019
National
Final Regulations
40 CFR 9 and 721 - Significant New Use Rules on Certain Chemical Substances
09/21/2012
National
Notices
40 CFR 1 - Chemical Substances and Mixtures Used in Oil and Gas Exploration or Production; TSCA Section 21 Petition; Reasons for Agency Response
07/11/2013
National
Proposed Regulations
40 CFR 2, 702, 703, 704, 707, 716, 717, 720, 723, 725, and 790 - Confidential Business Information Claims Under the Toxic Substances Control Act (TSCA)
05/12/2022
National
Final Regulations
40 CFR 2, 702, 703, 704, 707, 716, 717, 720, 723, 725, and 790 - Confidential Business Information Claims Under the Toxic Substances Control Act (TSCA)
06/07/2023
National
Final Regulations
40 CFR 271 - Modification of Significant New Uses for Oxazolidine, 3,3'-Methylenebis[5-methyl-,
07/30/2019
National
Proposed Regulations
40 CFR 271 - Proposed Modification of Significant New Uses of 1-Propene, 2,3,3,3-tetrafluoro-
05/31/2013
National
Proposed Regulations
40 CFR 271 - Significant New Use Rules on Certain Chemical Substances (22-1.5e); Correction
12/15/2022
National
Final Regulations
40 CFR 372 - Electronic Reporting of Toxics Release Inventory Data
08/27/2013
National
Final Regulations
40 CFR 372 - Implementing Statutory Addition of Certain Per- and Polyfluoroalkyl Substances; Toxic Chemical Release Reporting
06/22/2020
National
Final Regulations
40 CFR 700 - Fees for the Administration of the Toxic Substances Control Act (TSCA)
02/21/2024
National
Proposed Regulations
40 CFR 700 - Fees for the Administration of the Toxic Substances Control Act (TSCA); Extension of Comment Period
02/23/2021
National
Proposed Regulations
40 CFR 700 - Fees for the Administration of the Toxic Substances Control Act (TSCA
11/16/2022
National
Proposed Regulations
40 CFR 700 - Fees for the Administration of the Toxic Substances Control Act (TSCA)
01/11/2021
National
Final Regulations
40 CFR 702 - Procedures for Chemical Risk Evaluation Under the Toxic Substances Control Act (TSCA); Final Rule
05/03/2024
National
Final Regulations
40 CFR 704 and 712 - Small Manufacturer Definition Update for Reporting and Recordkeeping Requirements Under the Toxic Substances Control Act (TSCA) Section 8(a)
05/28/2020
National
Final Regulations
40 CFR 705 - Toxic Substances Control Act Reporting and Recordkeeping Requirements for Perfluoroalkyl and Polyfluoroalkyl Substances; Final Rule
10/11/2023
National
Proposed Regulations
40 CFR 705 - TSCA Section 8(a)(7) Reporting and Recordkeeping Requirements for Perfluoroalkyl and Polyfluoroalkyl Substances
06/28/2021
National
Proposed Regulations
40 CFR 705 - TSCA Section 8(a)(7) Reporting and Recordkeeping Requirements for Perfluoroalkyl and Polyfluoroalkyl Substances; Extension of Comment Period
08/03/2021
National
Final Regulations
40 CFR 710 - Procedures for Review of CBI Claims for the Identity of Chemicals on the TSCA Inventory
03/06/2020
National
Proposed Regulations
40 CFR 710 - Procedures for Review of CBI Claims for the Identity of Chemicals on the TSCA Inventory; Revisions to the CBI Substantiation Requirements
11/08/2019
National
Final Regulations
40 CFR 711 - Chemical Data Reporting
11/25/2020
National
Final Regulations
40 CFR 711 - Chemical Data Reporting; Extension of the 2020 Submission Period
04/09/2020
National
Final Regulations
40 CFR 711 - Chemical Data Reporting; Extension of the 2024 Submission Period
09/27/2024
National
Final Regulations
40 CFR 711 - Partial Exemption of Certain Chemical Substances From Reporting Additional Chemical Data
06/19/2014
National
Final Regulations
40 CFR 711 - TSCA Chemical Data Reporting Revisions Under TSCA Section 8(a)
04/09/2020
National
Final Regulations
40 CFR 712, 716, 720, 721, 723, 725, 766, 790, and 799 - Electronic Reporting Under the Toxic Substances Control Act
12/04/2013
National
Final Regulations
40 CFR 713 - Response to Vacatur of Certain Provisions of the Mercury Inventory Reporting Rule
11/08/2021
National
Final Regulations
40 CFR 716 - Health and Safety Data Reporting
12/28/2012
National
Final Regulations
40 CFR 716 - Health and Safety Data Reporting; Addition of 20 High-Priority Substances and 30 Organohalogen Flame Retardants
06/29/2021
National
Final Regulations
40 CFR 716 - Health and Safety Data Reporting; Addition of 20 High-Priority Substances and 30 Organohalogen Flame Retardants; Extension of Submission Deadline
10/01/2021
National
Final Regulations
40 CFR 716 - Health and Safety Data Reporting; Addition of Certain Chemicals
12/03/2012
National
Proposed Regulations
40 CFR 720, 721, 723, and 725 - Updates to New Chemicals Regulations Under the Toxic Substances Control Act (TSCA)
05/26/2023
National
Proposed Regulations
40 CFR 720, 721, 723, and 725 - Updates to New Chemicals Regulations Under the Toxic Substances Control Act (TSCA); Extension of Comment Period
07/19/2023
National
Final Regulations
40 CFR 721 - Significant New Use Rules on Certain Chemical Substances, Technical Correction
12/23/2016
National
Proposed Regulations
40 CFR 721 - EPA Withdraws a Significant New Use Rule for Certain Chemical Substances
03/26/2014
National
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